7 Best Free Online Allele Frequency Calculator Websites

Here is a list of the best free online Allele Frequency Calculator websites. An allele is a gene variant. Every gene has two variants making it 2 alleles per chromosome. The alleles are inherited from the parent. One allele always comes from the mother and the one from the father. Allele frequency describes how often a particular allele can be found in a population. With the allele frequency, you can calculate the chances that you and your partner are carriers of a genetic disease that may affect your children. Before moving forward, here are some useful definitions that one should know:

  • p – frequency of the wild (healthy) allele
  • q – frequency of the mutant (sick) allele
  • p² – frequency of people without the disease in the population (2 healthy alleles)
  • q² – frequency of people with the disease in the population (2 mutant alleles)
  • 2pq – frequency of people without the disease in the population (1 mutant, 1 healthy allele)

An Allele Frequency Calculator allows you to calculate the chances of being a carrier of a certain genetic trait. To calculate allele frequency, you need to know the frequency of the disease either in percentage or proportion. Alternatively, you must know the observed values of the genotypes. There are two types of calculators in this post. You can go through the post and check them out in detail.

My Favorite Online Allele Frequency Calculator

OmniCalculator is my favorite website on this list to calculate allele frequency. It is quite simple to use and gives you the allele frequency from a proportion or percentage of the population.

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OmniCalculator.com

OmniCalculator.com has a free online allele frequency calculator. This calculator takes the Frequency of the disease in the population in proportion or percentage. From that, it determines the Heathy (p) and Mutant (q) allele frequency. Along with the allele frequency, it also shows the carrier frequency. This implies how many people have mutant alleles out of a group of people. Calculations also include People with two healthy alleles (p²), people with two mutant alleles (q²), and People with one healthy, and one mutant allele (2pq).

How to calculate Allele Frequency with OmniCalculator?

  • Go to this calculator using the link given below.
  • Select either the Percentage or Proportion option as per your requirement.
  • Then enter the occurrence of the disease as per your selection.
  • This shows the Healthy and Mutant Allele Frequency.

Highlights:

  • This calculator can calculate allele frequency from proportion or percentage.
  • It shows the Heathy (p) allele frequency and Mutant (q) allele frequency.
  • It also calculates the carrier frequency of the mutant allele along with ,, and 2pq.

Perinatology.com

Perinatology.com offers a free online allele frequency calculator. This calculator uses the Hardy-Weinberg equation to estimate the frequency of the carrier state (2pq) for an autosomal recessive trait. All you have to do is add the population that has recessive traits either in percentage or in proportion. With that, this calculator gives you the frequency of wild-type allele (p), frequency of a mutant allele (q), and frequency of people without the disease in the population (2pq).

How to calculate Allele Frequency with Perinatology?

  • Open this calculator using the link given below.
  • Select the percentage or proportion option and then add your value.
  • After that click the Calculate button to get the results.

Highlights:

  • This calculator can calculate allele frequency from proportion or percentage.
  • It shows the Wild (p) allele frequency and Mutant (q) allele frequency.
  • It also calculates the carrier frequency of the mutant allele along with ,, and 2pq.

WpCalc.com

WpCalc.com has an online Equilibrium Hardy-Weinberg. You can use this calculator to determine the allele frequency. To do that, you have to provide the values of the Common Homozygotes, Heterozygotes, and Rare Homozygotes. From that, it calculates the expected common homozygotes, expected heterozygotes, expected rare homozygotes, and the frequency range of the 2 (p and q) alleles from the observed genotypes.

How to calculate Allele Frequency with WpCalc?

  • Use the link given below to open this calculator in your browser.
  • Enter the Common Homozygotes, Heterozygotes, and Rare Homozygotes values into the calculator.
  • Then click the Calculate button to get the results.

Highlights:

  • This calculator can calculate allele frequency from Common Homozygotes, Heterozygotes, and Rare Homozygotes.
  • It shows the Wild (p) allele frequency and Mutant (q) allele frequency.
  • It also calculates Chi-squared (chi²) along with the expected and observed genotypes.

Had2Know.org

Had2Know.org is a free website where you can use the Hardy-Weinberg Equilibrium calculator to determine the 2 Alleles. This calculator calculates the frequency range of the 2 (p & q) alleles from the observed genotypes. You can get that by adding the observed values of the AA, AAB, and BB genotypes. Along with the allele frequency, this calculator also calculates expected genotypes.

How to calculate Allele Frequency with Had2Know?

  • Use the link given below to open this calculator in your browser.
  • Enter the observed values of AA, AB, and BB genotypes.
  • Then click the Calculate button to get the results.

Highlights:

  • This calculator can calculate allele frequency from observed Genotypes.
  • It shows the Wild (p) allele frequency and Mutant (q) allele frequency.
  • It also calculates Chi-squared (chi²) along with the expected genotypes.

ihh.kvl.dk

ihh.kvl.dk is another website with a free online allele frequency calculator. This calculator performs the calculation of the Chi-square test for deviation from Hardy-Weinberg equilibrium. To do that, you have to provide the observed values of the genotypes. With that, you get the expected values of each genotype along with the chi, N, and allele frequency.

How to calculate Allele Frequency with ihh.kvl.dk?

  • Follow the link given below to open this calculator in your browser.
  • Enter the observed values of AA, AB, and BB genotypes.
  • Then click the Calculate button to get the results.

Highlights:

  • This calculator can calculate allele frequency from observed Genotypes.
  • It shows the Wild (p) allele frequency and Mutant (q) allele frequency.
  • It also calculates Chi-squared along with the expected genotypes and more.

Gene-Calc.pl

Gene-Calc.pl offers a free online allele frequency calculator. This calculator is based on the Hardy-Weinberg law. It checks the compliance between the observed and expected number of genotypes. You have to enter the value observed genotypes including Homozygotes, Heterozygotes, and Rare Homozygotes. For the input data, it shows you the results containing expected values, chi-square value, and of course, allele frequency.

How to calculate Allele Frequency with Gene-Calc.pl?

  • Use the link given below to open this calculator in your browser.
  • Enter the Homozygotes, Heterozygotes, and Rare Homozygotes values into the calculator.
  • Then click the Calculate button to get the results.

Highlights:

  • This calculator can calculate allele frequency from Homozygotes, Heterozygotes, and Rare Homozygotes.
  • It shows the allele frequency (p and q).
  • It also calculates Chi-squared (chi²) along with the expected and observed genotypes and more.

EasyCalculation.com

EasyCalculation is yet another free website where you can calculate the allele frequency. This website has a simple calculator based on the Hardy-Weinberg equation. It calculates the allele frequency (p and q) from the observed genotypes. That means you have to provide the values of Common Homozygotes, Heterozygotes, and Rare Homozygotes. With that, this calculator gives you the p allele frequency and q allele frequency.

How to calculate Allele Frequency with EasyCalculation?

  • Follow the link given below to open this calculator in your browser.
  • Enter the values of Common Homozygotes, Heterozygotes, and Rare Homozygotes  into the calculator.
  • Then click the Calculate button to get the results.

Highlights:

  • This calculator can calculate allele frequency from observed genotypes.
  • It shows the Wild (p) allele frequency and Mutant (q) allele frequency.
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